Journal article
The future burden of head and neck cancers attributable to modifiable behaviors in Australia: A pooled cohort study
MA Laaksonen, K Canfell, RJ MacInnis, E Banks, JE Byles, GG Giles, DJ Magliano, JE Shaw, V Hirani, TK Gill, P Mitchell, RG Cumming, U Salagame, CM Vajdic
Cancer Epidemiology Biomarkers and Prevention | Published : 2021
Abstract
Background: Estimates of future burden of cancer attributable to current modifiable causal exposures can guide cancer prevention. We quantified future head and neck cancer burden in Australia attributable to individual and joint causal exposures, and assessed whether these burdens differ between population subgroups. Methods: We estimated the strength of the associations between exposures and head and neck cancer using adjusted proportional hazards models from pooled data from seven Australian cohorts (N ¼ 367,058) linked to national cancer and death registries and estimated exposure prevalence from the 2017 to 2018 Australian National Health Survey. We calculated population attributable fra..
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Funding Acknowledgements
We thank the participating cohort studies and surveys and their participants for the data for this cohort consortium. Specific details of funding and data sources for the 45 and Up Study and the Australian Longitudinal Study on Women's Health are available at www.saxinstitute.org.au/our-work/45-up-study/for-partners/and www.alswh.org. Cohort recruitment for the Melbourne Collaborative Cohort Study (MCCS) was funded by Cancer Council Victoria (http://www.cancervic.org.au/) and VicHealth (https://www.vichealth.vic.gov.au/). The MCCS was further supported by Australian National Health and Medical Research Council grants 209057 and 396414 and by infrastructure provided by Cancer Council Victoria. The MCCS was made possible by the contribution of many people, including the original investigators, the teams that recruited the participants and continue working on follow-up, and the many thousands of Melbourne residents who continue to participate in the study. The CHAMP study is funded by the NHMRC(ID301916) and the Ageing and Alzheimer's Institute. We acknowledge the assistance of the AIHW Data Linkage Unit for undertaking the data linkage to the Australian Cancer Database and the National Death Index, and the AIHW Cancer Data and Monitoring Unit for providing the cancer incidence projections. We also thank the Australian Bureau of Statistics (ABS) for providing access to the National Health Survey data via the ABS DataLab and the ABS staff for their assistance with the analysis. This work was supported by the National Health and Medical Research Council of Australia (ID1060991). The National Health and Medical Research Council of Australia also supported Dr. M.A. Laaksonen (ID1053642), Prof. K. Canfell (ID1082989), Prof. E. Banks (ID1136128), Prof. J.E. Shaw (ID1079438), and Prof. D.J. Magliano (ID1118161). Dr M.A. Laaksonen was additionally supported by the Cancer Institute New South Wales (ID13/ECF/1-07, 2019/CDF1022).